News &amp; Updates

A 42-year-old male was hospitalized with a 2-week history of persistent fever, generalized maculopapular rash, and right cervical lymphadenopathy. His medical history and family history were unremarkable.

Use of a C5 inhibitor in a patient with AOSD complicated by atypical haemolytic uraemic syndrome

Claim defended over alleged misdiagnosis

It is important for doctors to consider patient referral to an appropriate specialty when necessary. This article highlights doctors’ responsibility to explain the reasoning for differential diagnosis and future management strategies in medical records, with a case study illustrating how medical defence organizations may provide assistance.

Claim defended over alleged misdiagnosis

Corticosteroid elimination with anti–IL-5 antibody in two patients with idiopathic HES

A 45-year-old male presented with generalized urticaria in September 2020. He had no past history of allergies, but had transient autoimmune thyroiditis in 2018, which subsequently resolved.

Corticosteroid elimination with anti–IL-5 antibody in two patients with idiopathic HES

Transthyretin amyloid cardiomyopathy: Tips for early diagnosis and treatment updates

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, fatal condition that predominantly affects older adults. The prognosis is poor, with a median overall survival (OS) of 3–5 years. The condition is often underrecognized or misdiagnosed due to low disease awareness and fragmented knowledge among healthcare professionals across specialties. This article provides practical advice for early diagnosis and treatment, with a focus on 5-year OS data from the ATTR-ACT trial of tafamidis and key recommendations from the 2023 American College of Cardiology (ACC) guidelines.

Transthyretin amyloid cardiomyopathy: Tips for early diagnosis and treatment updates

Clinical role of oral bempedoic acid in LDL-C management

LDL-cholesterol (LDL-C) reduction is the key to preventing and treating atherosclerotic cardiovascular disease (ASCVD). Recent guidelines advocate aggressive LDL-C lowering in individuals at high or very high cardiovascular (CV) risk. At the Advances in Medicine 2024 conference, Dr Chu-Pak Lau, Specialist in Cardiology, discussed the clinical role of non-statin lipid-lowering therapies (LLTs), including oral bempedoic acid as a single agent or in fixed-dose combination (FDC) with ezetimibe, in patients who have failed to achieve guideline-recommended LDL-C targets or have statin intolerance.

Clinical role of oral bempedoic acid in LDL-C management

More evidence strengthens link between meat, poultry and T2D

Initial mobility assessment in VTE risk stratification lacks accuracy

Initial clinical mobility assessments during venous thromboembolism (VTE) risk evaluation do not seem to convey patient mobility during their hospital stay, reveals a study.

Initial mobility assessment in VTE risk stratification lacks accuracy

27 Aug 2024

Many infant products sold in Southeast Asia are ultraprocessed: study

27 Aug 2024 by

Several products in the Southeast Asia (SEA) region that are being marketed for infants and young children are considered ultraprocessed and contain certain additives, reveals a recent study. In addition, many of these additives are banned by Codex Alimentarius.

Many infant products sold in Southeast Asia are ultraprocessed: study

STEMI criteria show similar accuracy in right BBB, non-BBB patients

The ECG criteria used for identifying patients with ST-elevation myocardial infarction (STEMI) demonstrates similar diagnostic accuracy in right bundle branch block (BBB) and non-BBB patients, according to a study.

STEMI criteria show similar accuracy in right BBB, non-BBB patients

27 Aug 2024

Virtual reality noninferior to sedation for procedure-related pain, anxiety

During painful procedures, a virtual reality (VR) intervention appears to be as good as sedation in terms of alleviating pain and anxiety but is safer and associated with a shorter recovery period, according to a study.

Virtual reality noninferior to sedation for procedure-related pain, anxiety