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Sildenafil shows promise as treatment for Alzheimer’s disease

15 Aug 2024 by

Sildenafil, a phosphodiesterase type 5 inhibitor, can be a potential treatment for Alzheimer’s disease (AD), as shown in real-world data, AD patient-induced pluripotent stem cells (iPSC)-derived neuron models, and in vivo transgenic mouse model observations, according to a study presented at AAIC 2024.

Sildenafil shows promise as treatment for Alzheimer’s disease

15 Aug 2024

Filgrastim tied to higher ACR burden in lung transplant recipients

15 Aug 2024

Use of filgrastim among lung transplant recipients (LTRs) for the treatment of neutropenia contributes to an increased burden of acute cellular rejection (ACR) and a reduced time to ACR, but not to an increased likelihood of ACR at 6 months, a study has shown.

Filgrastim tied to higher ACR burden in lung transplant recipients

15 Aug 2024

Multistrain probiotics do not reduce multidrug-resistant organisms in preemies

14 Aug 2024

In preterm infants, the use of multistrain probiotics does not appear to prevent colonization with multidrug-resistant organisms or highly epidemic bacteria (MDRO+), as shown in the phase III PRIMAL* trial.

Multistrain probiotics do not reduce multidrug-resistant organisms in preemies

14 Aug 2024

Add-on olanzapine augments nausea, vomiting control during chemo cycles

14 Aug 2024 by

Adding olanzapine to prophylactic antiemetic medications appeared to substantially improve nausea and vomiting control among patients receiving moderately emetogenic chemotherapy (MEC) regimens in a phase III randomized clinical trial.

Add-on olanzapine augments nausea, vomiting control during chemo cycles

14 Aug 2024

Education package improves pharmacist knowledge, confidence on HIV management

14 Aug 2024

A pharmacy-specific, foundational HIV management education package can help improve pharmacist knowledge in HIV management and self-reported confidence in managing this specialty area, suggests a recent study.

Education package improves pharmacist knowledge, confidence on HIV management

14 Aug 2024

Epilepsy ups maternal, perinatal risks in pregnant women

14 Aug 2024

Pregnant women with epilepsy face considerably greater risk of severe morbidity as well as maternal and perinatal mortality, according to a study.

Epilepsy ups maternal, perinatal risks in pregnant women

14 Aug 2024

Add-on dapagliflozin of no help in critically ill patients with acute organ dysfunction

13 Aug 2024

In the treatment of critically ill patients with acute organ dysfunction, use of the SGLT-2 inhibitor dapagliflozin in addition to standard care does not appear to improve clinical outcomes, according to a study.

Add-on dapagliflozin of no help in critically ill patients with acute organ dysfunction

13 Aug 2024

The next Berlin patient: 7th to join pool of HIV patients achieving sustained remission

13 Aug 2024 by

A new patient achieves sustained HIV remission – the seventh in the world – following stem cell therapy for blood cancer and after stopping antiretroviral therapy (ART), adding to the roster of individuals with HIV who are inching their way towards a potential cure.

The next Berlin patient: 7th to join pool of HIV patients achieving sustained remission

13 Aug 2024

Cytisinicline for vaping cessation turns in promising result in phase II trial

13 Aug 2024

Treatment with cytisinicline for 12 weeks, in addition to behavioural support, is well tolerated and appears to help e-cigarette users to quit vaping, according to the results of the phase II ORCA-V1 trial.

Cytisinicline for vaping cessation turns in promising result in phase II trial

13 Aug 2024

Dabrafenib plus trametinib boasts high pathological response for stage III melanoma

12 Aug 2024

Pathological response rates are high for neoadjuvant dabrafenib plus trametinib among patients with stage III melanoma, but recurrence-free survival (RFS) rates are low, reports a study.

Dabrafenib plus trametinib boasts high pathological response for stage III melanoma

12 Aug 2024

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Sildenafil shows promise as treatment for Alzheimer’s disease

Sildenafil shows promise as treatment for Alzheimer’s disease

Filgrastim tied to higher ACR burden in lung transplant recipients

Filgrastim tied to higher ACR burden in lung transplant recipients

Multistrain probiotics do not reduce multidrug-resistant organisms in preemies

Multistrain probiotics do not reduce multidrug-resistant organisms in preemies

Add-on olanzapine augments nausea, vomiting control during chemo cycles

Add-on olanzapine augments nausea, vomiting control during chemo cycles

Education package improves pharmacist knowledge, confidence on HIV management

Education package improves pharmacist knowledge, confidence on HIV management

Epilepsy ups maternal, perinatal risks in pregnant women

Epilepsy ups maternal, perinatal risks in pregnant women

Add-on dapagliflozin of no help in critically ill patients with acute organ dysfunction

Add-on dapagliflozin of no help in critically ill patients with acute organ dysfunction

The next Berlin patient: 7th to join pool of HIV patients achieving sustained remission

The next Berlin patient: 7th to join pool of HIV patients achieving sustained remission

Cytisinicline for vaping cessation turns in promising result in phase II trial

Cytisinicline for vaping cessation turns in promising result in phase II trial

Dabrafenib plus trametinib boasts high pathological response for stage III melanoma

Dabrafenib plus trametinib boasts high pathological response for stage III melanoma