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4F-PCC safe, effective in factor Xa inhibitor-related bleedings

06 Apr 2023

Treatment with four-factor prothrombin complex concentrate (4F-PCC) appears safe and effective for patients with factor Xa inhibitor-associated bleeding events, suggests a recent study.

4F-PCC safe, effective in factor Xa inhibitor-related bleedings

06 Apr 2023

Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep

06 Apr 2023

A smartphone-based Chinese culture-adapted digital cognitive behavioural therapy for insomnia (DCBT-I) appears beneficial, producing improvements in the severity of insomnia as compared with sleep education, according to a study.

Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep

06 Apr 2023

Apremilast provides skin clearance in paediatric psoriasis

06 Apr 2023 by

Treatment with apremilast showed clear or almost clear skin in paediatric patients with moderate-to-severe plaque psoriasis, according to the SPROUT study presented at AAD 2023.

Apremilast provides skin clearance in paediatric psoriasis

06 Apr 2023

Focused ultrasound ablation improves motor function in Parkinson’s

05 Apr 2023

Patients with Parkinson’s disease (PD) who have undergone unilateral focused ultrasound ablation of the internal segment of globus pallidus show improved motor function or reduced dyskinesia over a period of 3 months, although the procedure comes with adverse events, according to a study.

Focused ultrasound ablation improves motor function in Parkinson’s

05 Apr 2023

High marks for modified-release oral PDE4 inhibitor in moderate-to-severe psoriasis

05 Apr 2023 by

The modified-release formulation of novel oral phosphodiesterase-4 (PDE4) inhibitor orismilast shows therapeutic potential in adults with moderate-to-severe psoriasis, with high rates of clinical response as compared with placebo, according to data from the phase IIb IASOS trial presented at AAD 2023.

High marks for modified-release oral PDE4 inhibitor in moderate-to-severe psoriasis

05 Apr 2023

Medicare Advantage affects readmission/mortality ranking of top-performing hospitals

05 Apr 2023

A US study reports about one in four top-performing hospitals being reclassified to a lower performance group when Medicare Advantage (MA) beneficiaries are included in the assessment of hospital readmission and mortality.

Medicare Advantage affects readmission/mortality ranking of top-performing hospitals

05 Apr 2023

Second-line bevacizumab plus irinotecan extends survival in glioblastoma

05 Apr 2023 by

The combination of bevacizumab and irinotecan (BEV+IRI) as second-line treatment of glioblastoma (GBM) results in better median progression-free (PFS) and overall survival (OS) when compared with historical controls, and its toxicity profile is comparable to published data, reports a study.

Second-line bevacizumab plus irinotecan extends survival in glioblastoma

05 Apr 2023

Cardiac arrest not uncommon during delivery hospitalization

05 Apr 2023

One cardiac arrest occurs for every 9,000 delivery hospitalizations, among which about seven in 10 women survive to be discharged from the hospital, according to a study. In addition, survival is lowest during hospitalizations with co-occurring disseminated intravascular coagulation (DIC).

Cardiac arrest not uncommon during delivery hospitalization

05 Apr 2023

Vitamin D supplementation of little help in reducing psoriasis severity

05 Apr 2023

Among individuals with psoriasis, oral vitamin D supplementation does not appear to have any favourable effect on disease severity for those with low 25-hydroxyvitamin D (25[OH]D) levels, as reported in a study.

Vitamin D supplementation of little help in reducing psoriasis severity

05 Apr 2023

Bariatric surgery tied to substantial weight loss in obese teens

05 Apr 2023 by

Metabolic and bariatric surgery (MBS) significantly reduced BMI in severely obese adolescents compared with intensive nonsurgical treatment in the AMOS2* study.

Bariatric surgery tied to substantial weight loss in obese teens

05 Apr 2023

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4F-PCC safe, effective in factor Xa inhibitor-related bleedings

4F-PCC safe, effective in factor Xa inhibitor-related bleedings

Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep

Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep

Apremilast provides skin clearance in paediatric psoriasis

Apremilast provides skin clearance in paediatric psoriasis

Focused ultrasound ablation improves motor function in Parkinson’s

Focused ultrasound ablation improves motor function in Parkinson’s

High marks for modified-release oral PDE4 inhibitor in moderate-to-severe psoriasis

High marks for modified-release oral PDE4 inhibitor in moderate-to-severe psoriasis

Medicare Advantage affects readmission/mortality ranking of top-performing hospitals

Medicare Advantage affects readmission/mortality ranking of top-performing hospitals

Second-line bevacizumab plus irinotecan extends survival in glioblastoma

Second-line bevacizumab plus irinotecan extends survival in glioblastoma

Cardiac arrest not uncommon during delivery hospitalization

Cardiac arrest not uncommon during delivery hospitalization

Vitamin D supplementation of little help in reducing psoriasis severity

Vitamin D supplementation of little help in reducing psoriasis severity

Bariatric surgery tied to substantial weight loss in obese teens

Bariatric surgery tied to substantial weight loss in obese teens