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Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

28 Dec 2021 by

The benefits in terms of prolonged disease-free survival (DFS) and reduced risk of recurrence with ovarian function suppression (OFS) persisted over 12–13 years in premenopausal women with hormone receptor-positive (HR+) breast cancer, according to new data from the TEXT and SOFT randomized trials presented at SABCS 2021.

Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

28 Dec 2021

No clear evidence linking foods to natural menopause onset

28 Dec 2021

Eating green and yellow vegetables in high amounts or a keeping vegetarian diet in general is associated with an earlier onset of natural menopause, whereas a low intake of alcohol and a high intake of some dairy products are linked to a later onset, according to the results of a meta-analysis. However, the associations have been inconsistent, and the findings overall are not replicated among the studies included.

No clear evidence linking foods to natural menopause onset

28 Dec 2021

Depression prevalent in children, adults with hidradenitis suppurativa

28 Dec 2021

Depression is not uncommon among children, adolescents, and adults with hidradenitis suppurativa (HS), reports a study, adding that periodic screening for depression may be necessary.

Depression prevalent in children, adults with hidradenitis suppurativa

28 Dec 2021

Omicron raises new fears

28 Dec 2021 by

The threat of Omicron is real, with scientists working at breakneck speed to better understand its virulence and potential ability to evade currently approved vaccines.

Omicron raises new fears

28 Dec 2021

Chronic wounds compromise health-related quality of life

28 Dec 2021 by

Chronic wounds, particularly arterial ulcers, severely impair patients’ health-related quality of life by restricting their mobility and self-care, and by causing pain, discomfort, anxiety, and depression, according to a recent Singapore study.

Chronic wounds compromise health-related quality of life

28 Dec 2021

COMMODORE trial steers gilteritinib to the fore of AML treatment

28 Dec 2021 by

Gilteritinib provided significant survival benefit and demonstrated a favourable safety and tolerability profile in Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukaemia (R/R FLT3mut+ AML) compared with salvage chemotherapy (SC), findings from the phase III COMMODORE trial suggest.

COMMODORE trial steers gilteritinib to the fore of AML treatment

28 Dec 2021

Interval between biopsy and RARP does not impact biochemical recurrence in prostate cancer

28 Dec 2021

A prolonged gap between biopsy and robot-assisted radical prostatectomy (RARP) does not significantly influence the likelihood of biochemical recurrence (BCR) in prostate cancer patients, even in those who are considered high-risk, a recent Japan study has found.

Interval between biopsy and RARP does not impact biochemical recurrence in prostate cancer

28 Dec 2021

Vulnerable patients may need more help in the COVID-19 pandemic era

28 Dec 2021 by

With the situation of the COVID-19 pandemic, it is clear that the SARS-CoV-2 virus will be with us for a long time. A media roundtable organized by Roche Malaysia recently discussed the various ways in which vulnerable patient populations can cope with living in a world where vaccinations alone may not be sufficient.

Vulnerable patients may need more help in the COVID-19 pandemic era

28 Dec 2021

Bathroom urgency could well predict UC severity

28 Dec 2021 by

Frequent bathroom urgency in patients with ulcerative colitis (UC) could well predict UC severity. Hence, it should be considered a UC-specific patient-reported outcome, said experts at AIBD 2021.

Bathroom urgency could well predict UC severity

28 Dec 2021

Apixaban in the management of nonvalvular atrial fibrillation in older patients: Clinical evidence and experience sharing

28 Dec 2021 by

Nonvalvular atrial fibrillation (NVAF) raises the risk of stroke by three to five times, particularly in older patients. Treating older patients with NVAF presents special challenges because of their elevated risks for both stroke and bleeding. This necessitates optimization of anticoagulant therapy by balancing efficacy and bleeding risk. Non-vitamin K antagonist oral anticoagulants (NOACs), such as apixaban, have shown advantages in safety and efficacy over warfarin, which has a very narrow therapeutic index. In an interview with Dr Soon Chao Yang, Cardiologist at The Heart Doctors Clinic, Mount Alvernia Hospital, Singapore, he shared insights on managing NVAF in older patients, as well as his experience with using apixaban in this special population.

Apixaban in the management of nonvalvular atrial fibrillation in older patients: Clinical evidence and experience sharing

28 Dec 2021

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Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

No clear evidence linking foods to natural menopause onset

No clear evidence linking foods to natural menopause onset

Depression prevalent in children, adults with hidradenitis suppurativa

Depression prevalent in children, adults with hidradenitis suppurativa

Omicron raises new fears

Omicron raises new fears

Chronic wounds compromise health-related quality of life

Chronic wounds compromise health-related quality of life

COMMODORE trial steers gilteritinib to the fore of AML treatment

COMMODORE trial steers gilteritinib to the fore of AML treatment

Interval between biopsy and RARP does not impact biochemical recurrence in prostate cancer

Interval between biopsy and RARP does not impact biochemical recurrence in prostate cancer

Vulnerable patients may need more help in the COVID-19 pandemic era

Vulnerable patients may need more help in the COVID-19 pandemic era

Bathroom urgency could well predict UC severity

Bathroom urgency could well predict UC severity

Apixaban in the management of nonvalvular atrial fibrillation in older patients: Clinical evidence and experience sharing

Apixaban in the management of nonvalvular atrial fibrillation in older patients: Clinical evidence and experience sharing