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Does the ACC pathway work for patients with chest pain?

10 Apr 2024

The expert consensus decision pathway recently published by the American College of Cardiology (ACC) has demonstrated its safety and efficacy in people with chest pain participating in an observational cohort study. However, those with coronary artery disease (CAD) may not benefit from such strategy.

Does the ACC pathway work for patients with chest pain?

10 Apr 2024

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024 by

The US Food and Drug Administration (FDA) has approved the TriClip device for transcatheter edge-to-edge repair (TEER) in patients with severe tricuspid regurgitation (TR) or a leaky heart valve who are not eligible for surgery.

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024 by

Treatment with plozasiran, an experimental small interfering–RNA drug that targets apolipoprotein C3 (APOC3) gene, helps regulate triglyceride levels, bringing them below the critical threshold associated with acute pancreatitis for most patients with severe hypertriglyceridemia, according to the phase IIb SHASTA-2* study.

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024

Aprocitentan gets FDA nod for uncontrolled HTN

10 Apr 2024 by

The US Food and Drug Administration (FDA) has approved aprocitentan for the treatment of uncontrolled hypertension (HTN) in adults.

Aprocitentan gets FDA nod for uncontrolled HTN

10 Apr 2024

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Gartisertib, an oral inhibitor of ataxia telangiectasia and Rad3-related protein (ATR), for patients with advanced solid tumours is well tolerated at lower doses, according to the results of a phase I study. However, unexpected liver toxicity prevents dose escalation and, in turn, limits the drug’s antitumour activity.

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Healthy diet fails to offset diabetes risk for short sleepers

09 Apr 2024

A recent study suggests that adopting a healthy diet does protect against the risk of developing type 2 diabetes (T2D) among people with habitual short sleep duration, according to a study.

Healthy diet fails to offset diabetes risk for short sleepers

09 Apr 2024

Statins linked to moderate increase in diabetes risk, but overall benefits bear more weight

09 Apr 2024 by

Statin therapy appears to result in a modest elevation in blood sugar levels, increasing the likelihood of diabetes development especially among people whose blood sugar levels are already near the diagnostic threshold, according to a meta-analysis.

Statins linked to moderate increase in diabetes risk, but overall benefits bear more weight

09 Apr 2024

Study identifies 24-hour warning signs for suicide attempts among teens

09 Apr 2024

Changes in emotion, cognition, and behaviour over a 24-hour period may tell risk of suicide attempts among adolescents, with suicidal communications and withdrawal from social and other activities identified as key warning signs, according to a study.

Study identifies 24-hour warning signs for suicide attempts among teens

09 Apr 2024

Infant microbiome formula improves eczema severity and QoL in preschool children

09 Apr 2024 by

A novel infant microbiome formula (SIM03) containing unique Bifidobacterium bifidum and Bifidobacterium breve strains improves eczema severity and quality of life (QoL) in preschool children, shows a study by the Chinese University of Hong Kong (CUHK).

Infant microbiome formula improves eczema severity and QoL in preschool children

09 Apr 2024

2 drugs in 1 pill better than complex regimens for HIV

09 Apr 2024 by

The combination of bictegravir and lenacapavir, taken orally once daily, performed better than current complex treatment regimens in the phase II ARTISTRY-1 trial of people with HIV who are virologically suppressed.

2 drugs in 1 pill better than complex regimens for HIV

09 Apr 2024

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Does the ACC pathway work for patients with chest pain?

Does the ACC pathway work for patients with chest pain?

TriClip device gets FDA nod for leaky heart valve

TriClip device gets FDA nod for leaky heart valve

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

Aprocitentan gets FDA nod for uncontrolled HTN

Aprocitentan gets FDA nod for uncontrolled HTN

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

Healthy diet fails to offset diabetes risk for short sleepers

Healthy diet fails to offset diabetes risk for short sleepers

Statins linked to moderate increase in diabetes risk, but overall benefits bear more weight

Statins linked to moderate increase in diabetes risk, but overall benefits bear more weight

Study identifies 24-hour warning signs for suicide attempts among teens

Study identifies 24-hour warning signs for suicide attempts among teens

Infant microbiome formula improves eczema severity and QoL in preschool children

Infant microbiome formula improves eczema severity and QoL in preschool children

2 drugs in 1 pill better than complex regimens for HIV

2 drugs in 1 pill better than complex regimens for HIV