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A phase II trial of cabozantinib demonstrates the study drug’s efficacy in patients with hepatocellular carcinoma (HCC) previously treated with immune checkpoint inhibitor (ICI) regimens.

Cabozantinib offers survival benefits to ICI-treated HCC patients

11 Aug 2024

Garsorasib shows therapeutic potential in KRASG12C-mutated NSCLC

The investigational garsorasib, a potent KRASG12C inhibitor, appears to induce high response rate while having a manageable safety profile in patients with previously treated KRASG12C-mutated non–small cell lung cancer (NSCLC), according to the results of a phase II study.

Garsorasib shows therapeutic potential in KRASG12C-mutated NSCLC

Several factors contribute to chronic cough in children

Factors such as asthma, nitrogen oxide (NO2), home remodelling history, environmental tobacco smoke (ETS), pet, mould, and age＜1 year appear to predispose children to chronic coughing, according to the results of a meta-analysis.

Several factors contribute to chronic cough in children

Bisphosphonates no help in hip osteoarthritis in women

Use of bisphosphonates in women appears to neither prevent the development of hip osteoarthritis (OA) or pain nor delay radiographic changes over a 4-year follow-up, as shown in a study.

Bisphosphonates no help in hip osteoarthritis in women

Score model predicts prognosis in older adults with pneumonia

A new prediction score model identifies older patients with community-onset pneumonia who are nearing the end of life and need advance care planning (ACP) practices, reports a study.

Score model predicts prognosis in older adults with pneumonia

10 Aug 2024

Early birth control pill use a red flag for endometriosis

Young women who start taking hormonal contraceptives early in life may be at increased risk of endometriosis, as suggested in a study.

Early birth control pill use a red flag for endometriosis

Short-term screen detox boosts mental health of children, teens

Within families, reducing leisure-time screen media use over 2 weeks can yield positive benefits for the mental health of children and adolescents, according to a secondary analysis of a cluster randomized clinical trial.

Short-term screen detox boosts mental health of children, teens

STI rates in high-risk populations curbed with doxycycline PrEP

09 Aug 2024 bởi

Pre-exposure prophylaxis (PrEP) with the antibiotic doxycycline helps to prevent sexually transmitted infections (STIs) in high-risk populations, including female sex workers and HIV-positive men who have sex with men (MSM), according to two small studies.

STI rates in high-risk populations curbed with doxycycline PrEP

Vitamin C may improve survival in low-risk myeloid malignancy

09 Aug 2024 bởi

Vitamin C deficiency is not uncommon among patients with haematological cancer, but vitamin C supplementation can help address this condition and even provide a survival benefit, suggests a study presented at EHA 2024.

Vitamin C may improve survival in low-risk myeloid malignancy

Faecal microbiota transplantation flops for Parkinson’s disease

In the treatment of Parkinson’s disease (PD), faecal microbiota transplantation (FMT) is safe but does not appear to deliver clinically meaningful improvements, according to a study.

Faecal microbiota transplantation flops for Parkinson’s disease