Testicular Cancer Disease Summary

Overview

Testicular cancer is a rare neoplasm that arises from the testis. It commonly presents as a painless testicular mass.

It has high prevalence in young and middle-aged men in the age of 15-40 years old.

It is a highly treatable disease with a high cure rate.

Testicular primary germ cell tumors coming from the malignant transformation of primordial germ cells make up 95% of all testicular cancer.

Orchiectomy is usually curative for stage I seminoma.

Goals of risk-directed chemotherapy are to obtain maximum efficacy with minimal toxicity in patients with good risk and a more effective therapy with tolerable toxicity in patients with intermediate and poor risk. Salvage treatment is considered second line therapy. It may be given to patients who failed to improve with first line therapy or those who have developed recurrence. Treatment is based on response to previous therapy, timing and location of relapse and tumor histology.

For further information regarding the management of Testicular Cancer, please refer to Disease Algorithm for the Treatment Guideline.